Insulin via Nasal Spray

While the pharmaceutical incumbents promote inhalable insulin as an alternative to jabs, Bentley Pharmaceuticals (NYSE: BNT), a small outfit based in New Hampshire has signed a commercialization and production deal for insulin delivered via nasal spray.  Carlos Velez has an interesting post looking at the significance of this news:

Bentley is developing an interesting alternative to inhaled insulin, which, while approved recently, has some folks concerned over potential lung side effects. It's entirely possible that the intranasal formulation Bentley has will cause some irritation, but I'd take that over the potential decrease in lung function any day. Although I still think achieving consistent bioavailability (the amount of insulin which reaches the circulation) is going to be problematic. Their formulation does have much higher bioavailability than inhaled, which will manifest itself as a smaller device (a good marketing angle) and less insulin per dose (lower COGS).

The deal is also interesting, as Velez notes, because Bentley is partnering with Biocon (53253.BO) an Indian company to produce the new product.  The major U.S. companies, therefore, are no longer are the gatekeepers to global commercialization and development for smaller companies.

There's not guarantee of this product's success, of course, but it's obvious that this is dynamic market, and investors betting that one company has it locked up may be in for surprises.

And in other nasal spray news, the first true pharmaceutical aphrodisiac, PT-141, is in Phase III trials.  You can read a somewhat safe-for-work article about it here.  Here is its wikipedia entry.  The company developing it is Palatin pharmaceuticals (AMEX: PTN).

Comments

[urispas]

Honesty, integrity and a persuasive mentality are the most important qualities of an elected official
http://prometrium.kadm.biz/index.php?qq=prometrium during pregnancy prometrium during pregnancy

See you

[9 dvd season simpsons]

An integrated, segregated society is better

[my-server]

meu site... queria que avaliassem e dessem opinioes!

[John]

Estou no último ano de Design na faculdade de belas artes de lisboa, mas, embora não tenha nada a ver com o curso que estou a tirar, tenho uma grande paixão pela biologia marinha, e já pensei várias vezes em tirar o curso de Biologia Marinha quando acabar o que estou a frequentar. Sei que vai ser dificil mas eu estou disposta a tentar. Por issso, se tiveream alguma informação (cursos existentes em portugal ou estrangeiro, etc) que me possa ser útil, agradecia que me enviassem para Muito Obrigada pela vossa atenção

[ann]

Blame the parents of a murderer parents for the crime

[superstar]

We are better off today than we were eight years ago

display panel telephone lcd microwave projector digital tape stereo superstar mexico canada sonic sound brand maker style radio automobile factory patent enterprise formula racing japan island asia pacific ocean korea

[free adult archive]

Agree with a flat tax system

[gaymovie access]

I haven't been up to much lately. So it goes. What can I say? I've just been letting everything wash over me recently, not that it matters. I just don't have much to say these days.

[liveprivate]

Parents have no right in spanking you - Or do they? That could be another persuasive speech topic

[teens xxx]

Spam e-mails should be, should not be outlawed - Or: can, can not be outlawed, are examples of persuasive speech topic variants

[bang boat latina]

I haven't been up to much recently, but whatever. I just don't have much to say lately. Basically nothing happening to speak of. So it goes. My mind is like a complete blank. Such is life.

[amateur first facial]

I can't be bothered with anything these days. I guess it doesn't bother me. What can I say?

[pass xxx gay]

It is never okay to lie, sometimes okay to lie

[Insulin Pen]

Of all diabetes remedies one of the most important is the insulin pen. This is your friend to help you stabilize your blood sugar and get it down. Novo has a wide variety of insulin pens.

[Herve Leger Dress]

men ended up skeptics as well as Deists; that they exclusively planned a new secular govt through an "unbreachable wall" involving religious organization along with point out; that they perhaps composed in the treaty while using Moslem land involving Tripoli a specific affirmation that will, contrary to The european union, your "United Claims is just not, in any impression, a new Alfredia land. " (So evidently realized ended up being your rule involving separating involving religious organization along with point out during those times that this treaty handed down The nation's lawmakers with virtually no controversy in that will offer, along with Us president Bob Adams closed the idea immediately, with virtually no worry who's may possibly put in danger the politics potential. )

[herve leger dress]

An integrated, segregated society is better. i will share it with my friends!

[Herve leger sale]

Agree with a flat tax system

[moncler shop 2012]

It's so nice to have you do all of the research for us. It makes our decision making so much easier!! Thanks.